cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer

BACKGROUND: Recently published data showed discrepancies beteween P53 cDNA and DNA sequencing in glioblastomas. We hypothesised that similar discrepancies may be observed in other human cancers. METHODS: To this end, we analyzed 23 colorectal cancers for P53 mutations and gene expression using both...

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Hauptverfasser: Szybka, Malgorzata, Zakrzewska, Magdalena, Rieske, Piotr, Pasz-Walczak, Grazyna, Kulczycka-Wojdala, Dominika, Zawlik, Izabela, Stawski, Robert, Jesionek-Kupnicka, Dorota, Liberski, Pawel P, Kordek, Radzislaw
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731783/
https://ncbi.nlm.nih.gov/pubmed/19671129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-278
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