Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors

Fentanyl is a frequently used and abused opioid analgesic and can cause internalization of mu opioid receptors (MORs). Receptor internalization modulates the signaling pathways of opioid receptors. Because changes in dendritic spines and synaptic AMPA receptors play important roles in addiction and...

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Hlavní autoři: Lin, Hang, Higgins, Paul, Loh, Horace H., Law, Ping-Yee, Liao, Dezhi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731771/
https://ncbi.nlm.nih.gov/pubmed/19295508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.34
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