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Mu-opioid receptors modulate the stability of dendritic spines

Opioids classically regulate the excitability of neurons by suppressing synaptic GABA release from inhibitory neurons. Here, we report a role for opioids in modulating excitatory synaptic transmission. By activating ubiquitously clustered μ-opioid receptor (MOR) in excitatory synapses, morphine caus...

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Detalhes bibliográficos
Main Authors: Liao, Dezhi, Lin, Hang, Law, Ping Yee, Loh, Horace H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545084/
https://ncbi.nlm.nih.gov/pubmed/15659552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406797102
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