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Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors
Fentanyl is a frequently used and abused opioid analgesic and can cause internalization of mu opioid receptors (MORs). Receptor internalization modulates the signaling pathways of opioid receptors. Because changes in dendritic spines and synaptic AMPA receptors play important roles in addiction and...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731771/ https://ncbi.nlm.nih.gov/pubmed/19295508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.34 |
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