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Simvastatin Protects against Amyloid β and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells
Increased deposition of amyloid β (Aβ) is characteristic for normal aging and human immunodeficiency virus-1 (HIV-1)-associated alterations of the central nervous system. In addition, both Aβ and HIV-1 are known to induce cellular oxidative stress and disruption of the blood-brain barrier (BBB). The...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731660/ https://ncbi.nlm.nih.gov/pubmed/18276775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.042028 |
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