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Simvastatin Protects against Amyloid β and HIV-1 Tat-Induced Promoter Activities of Inflammatory Genes in Brain Endothelial Cells

Increased deposition of amyloid β (Aβ) is characteristic for normal aging and human immunodeficiency virus-1 (HIV-1)-associated alterations of the central nervous system. In addition, both Aβ and HIV-1 are known to induce cellular oxidative stress and disruption of the blood-brain barrier (BBB). The...

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Bibliografski detalji
Glavni autori: András, Ibolya E., Rha, GeunBae, Huang, Wen, Eum, SungYong, Couraud, Pierre-Olivier, Romero, Ignacio A., Hennig, Bernhard, Toborek, Michal
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731660/
https://ncbi.nlm.nih.gov/pubmed/18276775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.042028
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