Adipocyte CREB Promotes Insulin Resistance in Obesity

Increases in adiposity trigger metabolic and inflammatory changes that interfere with insulin action in peripheral tissues, culminating in beta cell failure and overt diabetes. We found that the cAMP Response Element Binding protein (CREB) is activated in adipose under obese conditions, where it pro...

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Bibliografiske detaljer
Main Authors: Qi, Ling, Saberi, Maziyar, Zmuda, Erik, Wang, Yiguo, Altarejos, Judith, Zhang, Xinmin, Dentin, Renaud, Hedrick, Susie, Bandyopadhyay, Gautam, Hai, Tsonwin, Olefsky, Jerry, Montminy, Marc
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730923/
https://ncbi.nlm.nih.gov/pubmed/19254572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.01.006
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