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Adipocyte CREB Promotes Insulin Resistance in Obesity
Increases in adiposity trigger metabolic and inflammatory changes that interfere with insulin action in peripheral tissues, culminating in beta cell failure and overt diabetes. We found that the cAMP Response Element Binding protein (CREB) is activated in adipose under obese conditions, where it pro...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730923/ https://ncbi.nlm.nih.gov/pubmed/19254572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.01.006 |
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