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Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia
Cilia have been implicated in Hedgehog (Hh) and Wnt signaling in mouse but not in Drosophila. To determine whether the role of cilia is conserved in zebrafish, we generated maternal-zygotic (MZ) oval (ovl; ift88) mutants that lack all cilia. MZovl mutants display normal canonical and non-canonical W...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730366/ https://ncbi.nlm.nih.gov/pubmed/19700616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.041343 |
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