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Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development
Many ciliopathies have clinical features that include tooth malformations but how these defects come about is not clear. Here we show that genetic deletion of the motor protein Kif3a in dental mesenchyme results in an arrest in odontogenesis. Incisors are completely missing, and molars are enlarged...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988628/ https://ncbi.nlm.nih.gov/pubmed/24659776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034514528211 |
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