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Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development

Many ciliopathies have clinical features that include tooth malformations but how these defects come about is not clear. Here we show that genetic deletion of the motor protein Kif3a in dental mesenchyme results in an arrest in odontogenesis. Incisors are completely missing, and molars are enlarged...

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Autors principals: Liu, B., Chen, S., Cheng, D., Jing, W., Helms, J.A.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988628/
https://ncbi.nlm.nih.gov/pubmed/24659776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034514528211
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