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Foxp3 instability leads to the generation of pathogenic memory T cells in vivo
Regulatory T (T(reg)) cells play a central role in maintaining immune homeostasis. However, little is known about the stability of T(reg) cells in vivo. In this study, we demonstrate that a significant percentage of cells exhibited transient or unstable Foxp3 expression. These exFoxp3(+) T cells exp...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729804/ https://ncbi.nlm.nih.gov/pubmed/19633673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1774 |
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