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Self-antigen driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
Stable Foxp3 expression is crucial for regulatory T (Treg) cell function. We observed that antigen-driven activation and inflammation in the central nervous system (CNS) promoted Foxp3 instability selectively in the autoreactive Treg cells that expressed high Foxp3 levels before experimental autoimm...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912996/ https://ncbi.nlm.nih.gov/pubmed/24238343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.10.016 |
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