Self-antigen driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

Stable Foxp3 expression is crucial for regulatory T (Treg) cell function. We observed that antigen-driven activation and inflammation in the central nervous system (CNS) promoted Foxp3 instability selectively in the autoreactive Treg cells that expressed high Foxp3 levels before experimental autoimm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bailey-Bucktrout, Samantha L., Martinez-Llordella, Marc, Zhou, Xuyu, Anthony, Bryan, Rosenthal, Wendy, Luche, Herve, Fehling, Hans J., Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912996/
https://ncbi.nlm.nih.gov/pubmed/24238343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.10.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados