TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

Regulatory T cells (Tregs) maintain immune homeostasis by limiting inflammatory responses. TRAF6 plays a key role in the regulation of innate and adaptive immunity by mediating signals from various receptors including the T-cell receptor (TCR). T cell-specific deletion of TRAF6 has been shown to ind...

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Autors principals: Muto, Go, Kotani, Hitoshi, Kondo, Taisuke, Morita, Rimpei, Tsuruta, Sanae, Kobayashi, Takashi, Luche, Hervé, Fehling, Hans Joerg, Walsh, Matthew, Choi, Yongwon, Yoshimura, Akihiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772853/
https://ncbi.nlm.nih.gov/pubmed/24058613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074639
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