Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling

Tumor necrosis factor receptor–associated factor (TRAF)2 is a critical adaptor molecule for tumor necrosis factor (TNF) receptors in inflammatory and immune signaling. Upon receptor engagement, TRAF2 is recruited to CD40 and translocates to lipid rafts in a RING finger-dependent process, which enabl...

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Detalhes bibliográficos
Main Authors: Arron, Joseph R., Pewzner-Jung, Yael, Walsh, Matthew C., Kobayashi, Takashi, Choi, Yongwon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194023/
https://ncbi.nlm.nih.gov/pubmed/12370254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020774
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