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Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise

Growth factors in the brain are important to depression and it’s treatment and we assessed the ability of peripherally administered insulin-like growth factor-I (IGF-I) to influence behavior related to depression. We found that mice that received chronic IGF-I treatment showed antidepressant-like be...

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Autori principali: Duman, Catharine H., Schlesinger, Lee, Terwilliger, Rosemarie, Russell, David S., Newton, Samuel S., Duman, Ronald S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729431/
https://ncbi.nlm.nih.gov/pubmed/19056428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2008.11.016
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