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Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

Recent clinical studies demonstrate that serum levels of brain-derived neurotrophic factor (BDNF) are significantly decreased in patients with major depressive disorder (MDD) and that antidepressant treatments reverse this effect, indicating that serum BDNF is a biomarker of MDD. These findings rais...

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Detalhes bibliográficos
Main Authors: Schmidt, Heath D, Duman, Ronald S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955759/
https://ncbi.nlm.nih.gov/pubmed/20686454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.114
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