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Stress-induced neuronal CSF1 provokes microglia-mediated neuronal remodeling and depressive-like behavior

BACKGROUND: Chronic stress exposure causes neuronal atrophy and synaptic deficits in the medial prefrontal cortex (PFC), contributing to development of anxiety-and depressive-like behaviors. Concomitantly microglia in the PFC undergo morphological and functional changes following stress exposure, su...

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Detalles Bibliográficos
Publicado en:Biol Psychiatry
Main Authors: Wohleb, Eric S., Terwilliger, Rosemarie, Duman, Catharine H., Duman, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506225/
https://ncbi.nlm.nih.gov/pubmed/28697890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.05.026
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