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Neurobiology of Stress, Depression, and Rapid Acting Antidepressants: Remodeling Synaptic Connections

Stress and depression are associated with atrophy and loss of neurons in limbic and cortical brain regions that could contribute to the symptoms of depression. Typical monoamine reuptake inhibitor antidepressants have only modest efficacy and require long-term treatment, and are only weakly effectiv...

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Bibliographic Details
Published in:Depress Anxiety
Main Author: Duman, Ronald S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432471/
https://ncbi.nlm.nih.gov/pubmed/24616149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/da.22227
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