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Neurobiology of rapid acting antidepressants: convergent effects on GluA1-synaptic function
Efforts to develop efficacious antidepressant agents with novel mechanisms have largely unsuccessful since the 1950’s until the discovery of ketamine, an NMDA receptor antagonist that produces rapid and sustained antidepressant actions even in treatment resistant patients. This finding has ushered a...
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| Udgivet i: | Mol Psychiatry |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754322/ https://ncbi.nlm.nih.gov/pubmed/30894661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0400-x |
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