Llwytho...

Gatekeeping versus Promiscuity in the Early Stages of the Andrimid Biosynthetic Assembly Line

The antibiotic andrimid, a nanomolar inhibitor of bacterial acetyl coenzyme A carboxylase, is generated on an unusual polyketide/nonribosomal pep-tide enzyme assembly line in that all thiolation (T) domains/small-molecule building stations are on separate proteins. In addition, a transglutaminase ho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Magarvey, Nathan A., Fortin, Pascal D., Thomas, Paul M., Kelleher, Neil L., Walsh, Christopher T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728764/
https://ncbi.nlm.nih.gov/pubmed/18652473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800085g
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