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Harnessing natural product assembly lines: structure, promiscuity, and engineering
Many therapeutically relevant natural products are biosynthesized by the action of giant mega-enzyme assembly lines. By leveraging the specificity, promiscuity, and modularity of assembly lines, a variety of strategies have been developed that enable the biosynthesis of modified natural products. Th...
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| Published in: | J Ind Microbiol Biotechnol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753117/ https://ncbi.nlm.nih.gov/pubmed/26527577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-015-1704-8 |
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