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Total Synthesis of Bryostatin 16 via Atom Economical and Chemoselective Approaches

Atom economy1 and chemoselectivity2 constitute two of the major challenges for enhancement of synthetic efficiency. The syntheses of complex natural products constitute the most demanding arena for exploration of such principles. The combination of extraordinary promising biological activity and the...

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Bibliographic Details
Main Authors: Trost, Barry M., Dong, Guangbin
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728752/
https://ncbi.nlm.nih.gov/pubmed/19037312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07543
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