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Enhanced radiosensitisation of human glioma cells by combining inhibition of PARP with inhibition of Hsp90
Glioblastoma multiforme are the commonest primary brain tumour and are resistant to standard therapies. The non-dividing nature of normal brain provides an opportunity to enhance the therapeutic ratio by combining radiation with inhibitors of replication-specific DNA repair pathways. Based on our pr...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728724/ https://ncbi.nlm.nih.gov/pubmed/19671736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0201 |
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