Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remains < 40%, highligh...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Metab
Main Authors: Nile, Donna L., Rae, Colin, Walker, David J., Waddington, Joe Canning, Vincent, Isabel, Burgess, Karl, Gaze, Mark N., Mairs, Robert J., Chalmers, Anthony J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136224/
https://ncbi.nlm.nih.gov/pubmed/34011385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00258-5
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