Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remains < 40%, highligh...

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Dades bibliogràfiques
Publicat a:Cancer Metab
Autors principals: Nile, Donna L., Rae, Colin, Walker, David J., Waddington, Joe Canning, Vincent, Isabel, Burgess, Karl, Gaze, Mark N., Mairs, Robert J., Chalmers, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136224/
https://ncbi.nlm.nih.gov/pubmed/34011385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00258-5
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