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N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition
Holocarboxylase synthetase (HCS) catalyzes the binding of the vitamin biotin to carboxylases and histones. Carboxylases mediate essential steps in macronutrient metabolism. For example, propionyl-CoA carboxylase (PCC) catalyzes the carboxylation of propionyl-CoA in the metabolism of odd-chain fatty...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728463/ https://ncbi.nlm.nih.gov/pubmed/19157941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2008.12.006 |
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