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Putting Synthesis into Biology: A Viral View of Genetic Engineering through De Novo Gene and Genome Synthesis

The rapid improvements in DNA synthesis technology hold the potential to revolutionize biosciences in the near future. Traditional genetic engineering methods are template dependent and make extensive but laborious use of site-directed mutagenesis to explore the impact of small variations on an exis...

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Autors principals: Mueller, Steffen, Coleman, J. Robert, Wimmer, Eckard
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728443/
https://ncbi.nlm.nih.gov/pubmed/19318214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.03.002
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