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Putting Synthesis into Biology: A Viral View of Genetic Engineering through De Novo Gene and Genome Synthesis

The rapid improvements in DNA synthesis technology hold the potential to revolutionize biosciences in the near future. Traditional genetic engineering methods are template dependent and make extensive but laborious use of site-directed mutagenesis to explore the impact of small variations on an exis...

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Detalhes bibliográficos
Main Authors: Mueller, Steffen, Coleman, J. Robert, Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728443/
https://ncbi.nlm.nih.gov/pubmed/19318214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.03.002
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