Brefeldin A Inhibits Cell-Free, De Novo Synthesis of Poliovirus

Brefeldin A (BFA), an inhibitor of intracellular vesicle-dependent secretory transport, is a potent inhibitor of poliovirus RNA replication in infected cells. We have determined that the unknown mechanism of BFA inhibition of replication is reproduced in the cell-free poliovirus translation, replica...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Cuconati, Andrea, Molla, Akhteruzzaman, Wimmer, Eckard
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1998
Subjects:	Animal Viruses
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6456-6464.1998
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