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Brefeldin A Inhibits Cell-Free, De Novo Synthesis of Poliovirus

Brefeldin A (BFA), an inhibitor of intracellular vesicle-dependent secretory transport, is a potent inhibitor of poliovirus RNA replication in infected cells. We have determined that the unknown mechanism of BFA inhibition of replication is reproduced in the cell-free poliovirus translation, replica...

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Detalhes bibliográficos
Main Authors: Cuconati, Andrea, Molla, Akhteruzzaman, Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109807/
https://ncbi.nlm.nih.gov/pubmed/9658088
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