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Feasibility of Using a Bone-Targeted, Macromolecular Delivery System Coupled with Prostaglandin E(1) to Promote Bone Formation in Aged, Estrogen-Deficient Rats
PURPOSE: Macromolecular delivery systems have therapeutic uses because of their ability to deliver and release drugs to specific tissues. The uptake and localization of HPMA copolymers using Asp(8) as the bone-targeting moiety was determined in aged, ovariectomized (ovx) rats. PGE(1) was attached vi...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727931/ https://ncbi.nlm.nih.gov/pubmed/18758923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9706-0 |
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