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Morphine Enhances Microglial Migration through Modulation of P2X(4) Receptor Signaling
Opioids, although fundamental to the treatment of pain, are limited in efficacy by side effects including tolerance and hyperalgesia. Using an in vitro culture system, we report that morphine increased microglial migration via a novel interaction between μ-opioid and P2X(4) receptors, which is depen...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727471/ https://ncbi.nlm.nih.gov/pubmed/19176808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4595-08.2009 |
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