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Involvement of Spinal Microglial P2X(7) Receptor in Generation of Tolerance to Morphine Analgesia in Rats
Morphine loses analgesic potency after repeated administration. The underlying mechanism is not fully understood. Glia are thought to be involved in morphine tolerance, and P2X(7) purinergic receptor (P2X(7)R) has been implicated in neuron–glia communication and chronic pain. The present study demon...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632682/ https://ncbi.nlm.nih.gov/pubmed/20534852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5377-09.2010 |
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