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Central serotonergic neurons are differentially required for opioid analgesia but not for morphine tolerance or morphine reward
Opioids remain the most effective analgesics despite their potential adverse effects such as tolerance and addiction. Mechanisms underlying these opiate-mediated processes remain the subject of much debate. Here we describe opioid-induced behaviors of Lmx1b conditional knockout mice (Lmx1b(f/f/p)),...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964813/ https://ncbi.nlm.nih.gov/pubmed/17724336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705740104 |
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