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In situ adenovirus vaccination engages T effector cells against cancer
The efficacy of cancer-immunotherapy is limited because of central and peripheral immune-tolerance towards tumor-antigens. We propose a novel approach based on the fact that the immune-system has not evolved tolerance towards adenoviruses (Ads) and that Ads have not evolved efficient mechanisms for...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727281/ https://ncbi.nlm.nih.gov/pubmed/19481312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.03.074 |
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