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Effect of adenovirus mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on anti-tumor immune responses

Heat shock proteins such as gp96 have the ability to chaperone peptides and activate antigen presenting cells. In this study we tested whether adenovirus (Ad)-mediated overexpression of secreted or membrane-associated forms of gp96 in tumor cells would stimulate an anti-tumor immune response. Studie...

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Detalhes bibliográficos
Main Authors: Di Paolo, Nelson C., Tuve, Sebastian, Ni, Shaoheng, Hellström, Karl Erik, Hellström, Ingegerd, Lieber, André
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360184/
https://ncbi.nlm.nih.gov/pubmed/16424031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-2388
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