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Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells
Telomeres are thought to be maintained by the preferential recruitment of telomerase to the shortest telomeres. The extension of the G-rich telomeric strand by telomerase is also believed to be coordinated with the complementary synthesis of the C-strand by the conventional replication machinery. Ho...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726829/ https://ncbi.nlm.nih.gov/pubmed/19665970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.026 |
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