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Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells

Telomeres are thought to be maintained by the preferential recruitment of telomerase to the shortest telomeres. The extension of the G-rich telomeric strand by telomerase is also believed to be coordinated with the complementary synthesis of the C-strand by the conventional replication machinery. Ho...

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Autors principals: Zhao, Yong, Sfeir, Agnel J., Zou, Ying, Buseman, Christen M., Chow, Tracy T., Shay, Jerry W., Wright, Woodring E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726829/
https://ncbi.nlm.nih.gov/pubmed/19665970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.026
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