Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

The evolution of prostate cancer from an androgen-dependent state (ADPCa) to one that is androgen-independent (AIPCa) marks its lethal progression. The androgen receptor (AR) is essential in both, though its function in AIPCa is poorly understood. We have defined the direct AR-dependent target genes...

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Hoofdauteurs: Wang, Qianben, Li, Wei, Zhang, Yong, Yuan, Xin, Xu, Kexin, Yu, Jindan, Chen, Zhong, Beroukhim, Rameen, Wang, Hongyun, Lupien, Mathieu, Wu, Tao, Regan, Meredith M., Meyer, Clifford A., Carroll, Jason S., Manrai, Arjun Kumar, Jänne, Olli A., Balk, Steven P., Mehra, Rohit, Han, Bo, Chinnaiyan, Arul M., Rubin, Mark A., True, Lawrence, Fiorentino, Michelangelo, Fiore, Christopher, Loda, Massimo, Kantoff, Philip W., Liu, X. Shirley, Brown, Myles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726827/
https://ncbi.nlm.nih.gov/pubmed/19632176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.056
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