Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

The evolution of prostate cancer from an androgen-dependent state (ADPCa) to one that is androgen-independent (AIPCa) marks its lethal progression. The androgen receptor (AR) is essential in both, though its function in AIPCa is poorly understood. We have defined the direct AR-dependent target genes...

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Main Authors: Wang, Qianben, Li, Wei, Zhang, Yong, Yuan, Xin, Xu, Kexin, Yu, Jindan, Chen, Zhong, Beroukhim, Rameen, Wang, Hongyun, Lupien, Mathieu, Wu, Tao, Regan, Meredith M., Meyer, Clifford A., Carroll, Jason S., Manrai, Arjun Kumar, Jänne, Olli A., Balk, Steven P., Mehra, Rohit, Han, Bo, Chinnaiyan, Arul M., Rubin, Mark A., True, Lawrence, Fiorentino, Michelangelo, Fiore, Christopher, Loda, Massimo, Kantoff, Philip W., Liu, X. Shirley, Brown, Myles
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726827/
https://ncbi.nlm.nih.gov/pubmed/19632176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.056
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