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Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

We have found earlier that Tor1 binds to 5S rDNA chromatin but the functional significance has not been established. Here, we show that association with 5S rDNA chromatin is necessary for TOR complex 1 (TORC1) to regulate the synthesis of 5S ribosomal RNA and transfer RNAs (tRNAs) by RNA polymerase...

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Библиографические подробности
Главные авторы: Wei, Yuehua, Tsang, Chi Kwan, Zheng, X F Steven
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726700/
https://ncbi.nlm.nih.gov/pubmed/19574957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.179
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