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Sch9 partially mediates TORC1 signaling to control ribosomal RNA synthesis

TORC1 is a central regulator of ribosomal RNA synthesis. Here we report that Sch9 partially mediates TORC1 signaling to regulate pol I- and pol III-dependent transcription. Mechanistically, Sch9 is involved in hyperphosphorylation and cytoplasmic localization of Maf1, and for optimal synthesis of rR...

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Hlavní autoři: Wei, Yuehua, Zheng, X.F. Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023923/
https://ncbi.nlm.nih.gov/pubmed/19823048
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