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Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

We have found earlier that Tor1 binds to 5S rDNA chromatin but the functional significance has not been established. Here, we show that association with 5S rDNA chromatin is necessary for TOR complex 1 (TORC1) to regulate the synthesis of 5S ribosomal RNA and transfer RNAs (tRNAs) by RNA polymerase...

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Detalhes bibliográficos
Main Authors: Wei, Yuehua, Tsang, Chi Kwan, Zheng, X F Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726700/
https://ncbi.nlm.nih.gov/pubmed/19574957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.179
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