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Inhibition of aac(6′)-Ib-mediated amikacin resistance by nuclease-resistant external guide sequences in bacteria

Inhibition of bacterial gene expression by RNase P-directed cleavage is a promising strategy for the development of antibiotics and pharmacological agents that prevent expression of antibiotic resistance. The rise in multiresistant bacteria harboring AAC(6′)-Ib has seriously limited the effectivenes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Soler Bistué, Alfonso J. C., Martín, Fernando A., Vozza, Nicolás, Ha, Hongphuc, Joaquín, Jonathan C., Zorreguieta, Angeles, Tolmasky, Marcelo E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726421/
https://ncbi.nlm.nih.gov/pubmed/19666539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906529106
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