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External guide sequence technology: a path to development of novel antimicrobial therapeutics

RNase P is a ribozyme originally identified for its role in maturation of tRNAs by cleavage of precursor tRNAs (pre-tRNAs) at the 5′-end termini. RNase P is a ribonucleoprotein consisting of a catalytic RNA molecule and, depending on the organism, one or more cofactor proteins. The site of cleavage...

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Bibliografski detalji
Izdano u:Ann N Y Acad Sci
Glavni autori: Sala, Carol Davies, Soler-Bistué, Alfonso, Bonomo, Robert, Zorreguieta, Angeles, Tolmasky, Marcelo E.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600001/
https://ncbi.nlm.nih.gov/pubmed/25866265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12755
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