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External Guide Sequences Targeting the aac(6′)-Ib mRNA Induce Inhibition of Amikacin Resistance

The dissemination of AAC(6′)-I-type acetyltransferases have rendered amikacin and other aminoglycosides all but useless in some parts of the world. Antisense technologies could be an alternative to extend the life of these antibiotics. External guide sequences are short antisense oligoribonucleotide...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bistué, Alfonso J. C. Soler, Ha, Hongphuc, Sarno, Renee, Don, Michelle, Zorreguieta, Angeles, Tolmasky, Marcelo E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891410/
https://ncbi.nlm.nih.gov/pubmed/17387154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01500-06
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