Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

Pygo and BCL9/Legless transduce the Wnt signal by promoting the transcriptional activity of β-catenin/Armadillo in normal and malignant cells. We show that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless to bind specifically to the histone H3 tail met...

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Autores principales: Fiedler, Marc, Sánchez-Barrena, María José, Nekrasov, Maxim, Mieszczanek, Juliusz, Rybin, Vladimir, Müller, Jürg, Evans, Phil, Bienz, Mariann
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726290/
https://ncbi.nlm.nih.gov/pubmed/18498752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.03.011
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