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An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP

TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated by β-catenin following Wnt signaling. They control embryonic development and adult stem cell compartments, and their dysregulation often causes cancer. β-catenin-dependent transcription relies on the NPF motif...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Fiedler, Marc, Graeb, Michael, Mieszczanek, Juliusz, Rutherford, Trevor J, Johnson, Christopher M, Bienz, Mariann
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571689/
https://ncbi.nlm.nih.gov/pubmed/26312500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09073
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