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An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP
TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated by β-catenin following Wnt signaling. They control embryonic development and adult stem cell compartments, and their dysregulation often causes cancer. β-catenin-dependent transcription relies on the NPF motif...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571689/ https://ncbi.nlm.nih.gov/pubmed/26312500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09073 |
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