Selection and Characterization of Murine Monoclonal Antibodies to Staphylococcus aureus Iron-Regulated Surface Determinant B with Functional Activity In Vitro and In Vivo

In an effort to characterize important epitopes of Staphylococcus aureus iron-regulated surface determinant B (IsdB), murine IsdB-specific monoclonal antibodies (MAbs) were isolated and characterized. A panel of 12 MAbs was isolated. All 12 MAbs recognized IsdB in enzyme-linked immunosorbent assays...

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Detalhes bibliográficos
Main Authors: Brown, Martha, Kowalski, Rose, Zorman, Julie, Wang, Xin-min, Towne, Victoria, Zhao, Qinjian, Secore, Susan, Finnefrock, Adam C., Ebert, Tim, Pancari, Greg, Isett, Kevin, Zhang, Yuhua, Anderson, Annaliesa S., Montgomery, Donna, Cope, Leslie, McNeely, Tessie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725548/
https://ncbi.nlm.nih.gov/pubmed/19553551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00085-09
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