A Novel Staphylococcus aureus Vaccine: Iron Surface Determinant B Induces Rapid Antibody Responses in Rhesus Macaques and Specific Increased Survival in a Murine S. aureus Sepsis Model

Staphylococcus aureus is a major cause of nosocomial infections worldwide, and the rate of resistance to clinically relevant antibiotics, such as methicillin, is increasing; furthermore, there has been an increase in the number of methicillin-resistant S. aureus community-acquired infections. Effect...

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Main Authors: Kuklin, Nelly A., Clark, Desmond J., Secore, Susan, Cook, James, Cope, Leslie D., McNeely, Tessie, Noble, Liliane, Brown, Martha J., Zorman, Julie K., Wang, Xin Min, Pancari, Gregory, Fan, Hongxia, Isett, Kevin, Burgess, Bruce, Bryan, Janine, Brownlow, Michelle, George, Hugh, Meinz, Maria, Liddell, Mary E., Kelly, Rosemarie, Schultz, Loren, Montgomery, Donna, Onishi, Janet, Losada, Maria, Martin, Melissa, Ebert, Timothy, Tan, Charles Y., Schofield, Timothy L., Nagy, Eszter, Meineke, Andreas, Joyce, Joseph G., Kurtz, Myra B., Caulfield, Michael J., Jansen, Kathrin U., McClements, William, Anderson, Annaliesa S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418914/
https://ncbi.nlm.nih.gov/pubmed/16552052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2215-2223.2006
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