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Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model

We have previously shown that IsdB, a conserved protein expressed by Staphylococcus aureus, induces a robust antibody response which correlates with protection in a murine challenge model. Here we investigate the role of cellular immunity in IsdB mediated protection using lymphocyte deficient SCID m...

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Detalhes bibliográficos
Main Authors: Joshi, Amita, Pancari, Greg, Cope, Leslie, Bowman, Edward P., Cua, Daniel, Proctor, Richard A., McNeely, Tessie
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426080/
https://ncbi.nlm.nih.gov/pubmed/22327491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.18946
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